The syndrome of sex-linked hydrocephalus.

Bickers and Adams (1949) and Edwards, Norman and Roberts (1961) have presented detailed neuropathological examinations on two cases of hydrocephalus secondary to aqueductal stenosis in families with many hydrocephalic males. These, taken together, provide incontrovertible evidence of a specific syndrome with sex-linked recessive inheritance. In this paper further families are described in which the same disorder appears to be manifest, although the basic observation of the neuropathology has not been made.